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Back Matter Source: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, No. 22 (Oct. 26, 1999), pp. xi-xix Published by: National Academy of Sciences Stable URL: http://www.jstor.org/stable/49458 . Accessed: 07/05/2014 17:14 Your use of the JSTOR archive indicates your acceptance of the Terms & Conditions of Use, available at . http://www.jstor.org/page/info/about/policies/terms.jsp . JSTOR is a not-for-profit service that helps scholars, researchers, and students discover, use, and build upon a wide range of content in a trusted digital archive. We use information technology and tools to increase productivity and facilitate new forms of scholarship. For more information about JSTOR, please contact [email protected]. . National Academy of Sciences is collaborating with JSTOR to digitize, preserve and extend access to Proceedings of the National Academy of Sciences of the United States of America. http://www.jstor.org This content downloaded from 169.229.32.136 on Wed, 7 May 2014 17:15:00 PM All use subject to JSTOR Terms and Conditions
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Page 1: Back Matter

Back MatterSource: Proceedings of the National Academy of Sciences of the United States of America,Vol. 96, No. 22 (Oct. 26, 1999), pp. xi-xixPublished by: National Academy of SciencesStable URL: http://www.jstor.org/stable/49458 .

Accessed: 07/05/2014 17:14

Your use of the JSTOR archive indicates your acceptance of the Terms & Conditions of Use, available at .http://www.jstor.org/page/info/about/policies/terms.jsp

.JSTOR is a not-for-profit service that helps scholars, researchers, and students discover, use, and build upon a wide range ofcontent in a trusted digital archive. We use information technology and tools to increase productivity and facilitate new formsof scholarship. For more information about JSTOR, please contact [email protected].

.

National Academy of Sciences is collaborating with JSTOR to digitize, preserve and extend access toProceedings of the National Academy of Sciences of the United States of America.

http://www.jstor.org

This content downloaded from 169.229.32.136 on Wed, 7 May 2014 17:15:00 PMAll use subject to JSTOR Terms and Conditions

Page 2: Back Matter

Author Index OCTOBER 26, 1999

A Aaltonen, L. A. 12661 Abe, Y. 12333 Abel, G. 12766 Ackermann, M. 12697 Addo, M. F. 12257 Adema, G. J. 12697 Agafonov, D. E. 12345 Agnello, V. 12766 Aguilar-C6rdova, E.

12816 Ahrlund-Richter, L.

12749 Alessandrini, A. 12866 Alicot, E. 12708 Alt, F. W. 12713 Amalric, F. 12772 Ames, B. N. 12216 Amess, B. 12589 Anagnostaras, S. G.

12905 Andang, M. 12749 Anderson, D. M. 12839 Andrade-Gordon, P.

12257 Andronis, C. 12362 Arnold, F. H. 12305 Arnould, I. 12685 Artzt, K. 12605 Assman, G. 12685 Attygalle, A. B. 12251

B Bacheller, D. J. 12448 Baekkeskov, S. 12911 Baekkevold, E. S. 12772 Baer, K. 12860 Banerjee, P. K. 12905 Baneyx, G. 12518 Barbuch, R. 12655 Bard, M. 12655 Bartle, L. M. 12536 Baruch, D. 12743 Baud, F. 12494, 12500 Baylin, S. B. 12754 Bear, M. F. 12876 Beaudet, A. L. 12816 Becerra, J. X. 12626 Bee, J. 12553 Belinsky, S. A. 12754 Bender, J. 12691 Benke, D. 12860 Benson, J. A. 12860 Berger, J. S. 12959 Bergstrom, F. 12477 Berns, K. I. 12849 Bishai, W. R. 12844 Bissell, D. M. 12719

Blackburn, E. H. 12454 Blanas, E. 12703 Bluethmann, H. 12860 Bock, J. B. 12227 Bodmer, W. F. 12553 Boettinger, E. 12595 Bonventre, J. V. 12866 Bor6n, T. 12778 Bourri6, B. 12855 Brandtzaeg, P. 12772 Brewer, H. B., Jr. 12685 Bribes, E. 12855 Britton, S. 12749 Broccardo, C. 12685 Brockman, M. A. 12708 Bronstein, S. M. 12384 Brooks, C. L., III 12512 Brown, P. O. 12833 Brusten, L. 12589 Buffet, P. A. 12743 Buratowski, R. M.

12542 Buratowski, S. 12542 Burbulis, I. E. 12929 Burgess, B. K. 12389 Burton, M. 12725

C Cahoon, E. B. 12935 Cairns, B. 12870 Calavetta, L. 12760 Calaycay, J. R. 12356 Caldwell, R. L. 12616 Camazine, S. 12611 Carbone, F. R. 12703 Carey, K. D. 12816 Carfi, A. 12379 Carlson, T. J. 12935 Carmen, A. A. 12356 Caron, M. G. 12222 Carroll, M. C. 12708 Carter, C. S. 12601 Cartwright, R. A. 12810 Casellas, P. 12855 Chan, J. 12887 Chan, K. 12731 Chang, L.-Y. 12760 Chao, C.-C. 12970 Chapple, C. 12328 Chen, C.-H. 12784,

12798 Chen, D. J. 12454 Chen, E. L. 12970 Chen, F. 12713 Chen, K. 12389 Chen, L. 12287 Cheng, X. 12394 Chester, A. E. 12887

Chihade, J. W. 12316 Chimini, G. 12685 Chittenden, T. 12536 Choi, C. Y. 12350 Chudnovsky, D. V.

12263 Chudnovsky, G. V.

12263 Chung, J. H. 12311 Classen, M. 12778 Clifford, T. 12394 Cole, P. A. 12418 Collmer, A. 12839 Colosi, P. 12725 Conaway, J. W. 12436 Conaway, R. C. 12436 Cook, G. A. 12935 Copenhagen, D. 12911 Couto, L. 12725 Cox, D. R. 12273 Csukai, M. 12798 Cunningham, J. 12725

D Da Costa, X. J. 12708 Daniels, M. J. 12923 Darrow, A. L. 12257 Davey, G. 12703 Davidson, L. 12713 Davies, S. C. 12589 Day, B. J. 12760 Dean, M. 12685 De Angelis, J. 12418 Debin, A. 12293 DeCamilli, P. 12559 Deich, J. 12394 de la Chapelle, A. 12661 DeLorey, T. M. 12905 Denefle, P. 12685 Deneubourg, J. L. 12611 Derian, C. K. 12257 DeRisi, J. 12833 D'Esposito, M. 12959 Dinger, M. 12685 Dionne, C. A. 12536 Dombrowski, J. E.

12947 Dong, F. 12448 Dorn, G. W., II 12798 Dozono, J. M. 12448 Drea, C. M. 12965 Duckett, D. R. 12384 Durand, D. 12293 Durst, K. L. 12822 Duverger, N. 12685 Dyall, J. 12849

E Eaves, A. 12804 Eaves, C. 12804 Eckardt, A. J. 12257 Eckstein, J. 12655 Edelmann, W. 12595 Eggert, J. H. 12269 Eisner, T. 12246, 12251 Elfahal, M. 12766 Elion, E. A. 12679 Elling, C. E. 12322 Elwyn, S. 12638 Emoto, K. 12400 Epelboim, J. 12953 Erdmann, M. V. 12616 Escalante-Alcalde, D.

12595 Esclangon, M. 12855 Essrich, C. 12860 Etienne, A. 12293

F Fanselow, M. S. 12905 Faull, K. F. 12424 Fedoroff, N. V. 12941 Feliu, J. 12772 Ferr6, P. 12737 Ferrini, R. 12713 Fink, G. R. 12530 Firestone, L. L. 12905 Fischer, M. B. 12708 Flavell, A. J. 12211 Foretz, M. 12737 Foufelle, F. 12737 Fouts, D. E. 12839 Fraefel, C. 12697 Fredrickson, D. S. 12685 Frerking, M. 12917 Fritschy, J.-M. 12860 Fujii, N. 12743 Funke, H. 12685 Fusai, T. 12743

G Gachotte, D. 12655 Gainetdinov, R. R.

12222 Galitski, T. 12530 Gamain, B. 12743 Gangal, M. 12394 Garcia, L. 12855 Garcia, L. R. 12430 Ge, J. 12339 George, J. 12719 Gerhard, M. 12778 Gerlai, R. 12870 Gershenson, A. 12305 Gilley, D. 12454

Girard, J.-P. 12772 Golan, D. E. 12583 Goldmacher, V. S.

12536 Goncharov, A. F. 12269 Goodwin, E. B. 12605 Graham, F. L. 12816 Gray, M. 0. 12784,

12798 Green, M. R. 12650 Green, R. M. 12362 Griffin, P. R. 12356 Grob, P. 12697 Grunstein, M. 12356 Gueron, S. 12240 Guichard, C. 12737 Guidotti, A. 12905 Gustafsson, J.-A. 12887 Gysin, J. 12743

H Hager, L. P. 12412 Hagglof, P. 12477 Hakoshima, T. 12333 Hall, R. A. 12559 Hall, S. E. 12935 Han, B. 12953 Han, J.-w. 12536 Harris, K. M. 12213 Harrison, S. D. 12548 Hatfield, R. D. 12328 Heath, W. R. 12703 Heeger, A. J. 12219 Heeger, P. S. 12219 Heinemann, S. F. 12667 Helgeson, R. 12287 Hemley, R. J. 12269 Herath, A. 12589 Herbert, A. 12465 Herman, J. G. 12754 Hernandez-Rivas, R.

12743 Herschlag, D. 12299 Heyer, J. 12595 Hiebert, S. W. 12822 Higashiyama, T. 12577 Hildeman, D. 12691 Hillis, D. M. 12616 Hinkula, J. 12749 Hirotsu, S. 12333 Hochachka, P. W. 12233 Hochschild, A. 12673 Hoekstra, W. J. 12257 Holder, M. T. 12616 Holmberg, M. T. 12661 Holst, B. 12322 Holyoake, T. 12804 Homanics, G. E. 12905

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Page 3: Back Matter

Hopfield, J. J. 12506 Hori, H. 12333 Hotchkiss, G. 12749 Hou, Y. 12822 Hsu, H.-L. 12454 Hu, L. A. 12559 Hurwitz, J. 12367

Igarashi, J. 12583 Imboden, P. 12833 Ishii, M. 12418 Iwai, K. 12436

J Jan, E. 12605 Jiang, X. 12804 Johansson, L. B.-A.

12477 Johnson, D. A. 12394 Johnson, R. E. 12224 Johnstone, R. A. 12644 Jordan, I. K. 12621 Joseph, C. M. 12275

K Kamura, T. 12436 Kan, Y. W. 12731 Kane, E. 12810 Kaplan, J. 12816 Kappler, J. 12691 Karavanic, I. 12281 Karlin, S. 12494, 12500 Karmon, E. 12269 Karolin, J. 12477 Kash, S. 12911 Kavalali, E. T. 12893 Kedersha, N. L. 12536 Kedl, R. M. 12691 Khalil, E. M. 12418 Kieff, E. D. 12536 Kim, Y. 12350 Kim, Y. H. 12350 Kinney, A. J. 12935 Klausner, R. D. 12436 Klingauf, J. 12893 Knapper, C. 12685 Knight, G. B. 12766 Knipe, D. M. 12708 Koch, C. 12685 Kochanek, S. 12816 Koehl, P. 12524 Kolb, V. A. 12345 Kong, D. 12367 Korach, K. S. 12887 Korpi, E. R. 12905 Koteliansky, V. E. 12719 Krieger, M. 12655 Kristensen, H.-H. 12833 Kucherlapati, R. 12595 Kuge, 0. 12400 Kuihne, R. 12465 Kuismanen, S. A. 12661 Kuroiwa, T. 12577 Kurts, C. 12703

L Lagenaur, C. 12905 Lander, E. S. 12530 Langdon, R. C. 12673 Larsson, S. 12749 Latham, G. J. 12448 Lee, B. N. 12679 Lee, C.-H. 12311 Lee, J.-K. 12367 Lee, J.-S. 12311 Lefkowitz, R. J. 12559 Leggett, M. 12923 Lehn, N. 12778 Leland, M. 12816 Leong, P. 12548 Levit-Gurevich, K.

12240 Levitt, M. 12524 Lew, A. M. 12697,

12703 Li, M. 12703 Li, Z. 12905 Lia, M. 12595 Lin, Y.-T. 12406 Lin-Chao, S. 12406 Lints, T. 12901 Liron, T. 12798 Liu, G. 12424 Liu, X. 12442 Lodish, H. F. 12442 Lopez, A. 12804 Lorenz, J. N. 12798 Loushin, C. 12605 Lowe, D. G. 12870 Lowenhaupt, K. 12465 Lu, Z.-L. 12953 Luischer, B. 12860 Lutterbach, B. 12822 Lutz, R. J. 12536

M Ma, M. 12708 McBranch, D. W. 12287 McComsey, D. F. 12257 McDevitt, H. 0. 12970 McDonald, J. F. 12621 McFarland, E. D. C.

12536 McGrew, J. 12379 McNew, J. A. 12565,

12571 Madhani, H. D. 12530 Maffrand, J.-P. 12855 Manabe, Y. C. 12844 Manoj, K. M. 12412 Mao, H.-k. 12269 Marchand, J. 12855 Marita, J. M. 12328 Marrack, P. 12691 Martinez-Romero, E.

12275 Maryanoff, B. E. 12257 Matsunaga, S. 12577 Matyunina, L. V. 12621 Mazmanian, S. K. 12424 Meinwald, J. 12246,

12251 Melton, R. B. 12923

Mi, Z.-P. 12905 Michel, T. 12583 Miehlke, S. 12778 Mihalek, R. M. 12905 Miller, H. P. 12459 Miller, J. F. A. P. 12703 Miller, L. H. 12743 Miller, W. E. 12559 Millor, J. 12611 Minato, N. 12436 Misumi, 0. 12577 Mitchell, R. 12725 Mitchell, T. 12691 Mitra, P. P. 12901 Mocarski, E. S. 12536 Mochly-Rosen, D.

12784, 12798 Modrich, P. 12384 Molineux, I. J. 12430 Monroe, R. J. 12713 Moon, K.-Y. 12367 Moran, N. A. 12638 Morehouse, H. 12542 Morgan, G. 12810 Morral, N. 12816 Moskowitz, M. A. 12866 Mroczko, M. 12412 Munson, G. P. 12828 Murphy, J. R. 12844 Murphy, M. R. 12311

N Nagahara, N. 12333 Nakai, H. 12725 Namura, S. 12866 Naudin, L. 12685 Nazimov, I. V. 12345 Neumayer, N. 12778 New, M. I. 12790 Ng-Eaton, E. 12442 Nguyen, H.-H. T. 12339 Nickel, W. 12571 Nicoll, R. 12911 Nicoll, R. A. 12917 Nishijima, M. 12400 Nishimura, Y. 12577 Nishino, T. 12333 Nottebohm, F. 12901 Novelli, M. R. 12553 Nuovo, G. J. 12754 Ny, T. 12477 Nystrom-Lahti, M.

12661

0 Ochman, H. 12638 Ogawa, S. 12887 O'Hare, M. J. 12589 Oishi, S. 12743 Okada, K. 12333 Oksenberg, D. 12257 Olsen, R. W. 12905 Olstein, D. H. 12876 O'Neal, W. 12816 Ong, M. S. 12362 Onuchic, J. N. 12512 Opperman, T. 12373 Osbourn, A. B. 12923

Oschkinat, H. 12465

p Packard, M. G. 12881 Page, M. J. 12589 Palmer, J. T. 12870 Palmiter, K. A. 12488 Palumbi, S. R. 12632 Palvadeau, Y. 12293 Panda, D. 12459 Papadopoulou, K. 12923 Parekh, R. 12589 Parks, R. J. 12816 Parlati, F. 12565, 12571 Parzy, D. 12743 Patel, M. 12760 Paunovic, M. 12281 Pause, A. 12436 Pearce, G. 12947 Pellegrino, M. A. 12650 Peltomaki, P. 12661 Pereira de Araujo, A. F.

12482 Perini, G. 12650 Perlstein, D. L. 12339 Petersen, C. 12911 Petersen, C. C. H.

12917 Peterson, K. M. 12685 Pettitt, P. B. 12281 Pfaff, D. W. 12887 Pham-Delegue, M.

12611 Phillips, D. A. 12275 Piccirilli, J. A. 12299 Piedra, P. A. 12816 Pietroni, P. 12448 Pitcher, J. A. 12559 Plaia, T. W. 12754 Postle, B. R. 12959 Pouvelle, B. 12743 Prabhakar, P. 12583 Prades, C. 12685 Prakash, L. 12224 Prakash, S. 12224 Prinz, C. 12778 Punkay, E. 12605

Q Quinlan, E. M. 12876 Quinlan, J. J. 12905

R Rad, R. 12778 Ralph, J. 12328 Rane, S. 12833 Ray, B. D. 12655 Raychaudhuri, S. 12367 Rees, W. 12691 Regnstr6m, K. 12389 Remaley, A. T. 12685 Reynolds, E. E. 12257 Rice, K. 12816 Rich, A. 12465 Ringstad, N. 12559 Ripp, K. G. 12935 Rollinson, S. 12810 Roman, B. 12810

Rook, M. S. 12471 Rosewell, I. 12553 Rosier, M. 12685 Rothman, J. E. 12565,

12571 Rottapel, R. 12230 Roulot, D. 12719 Rundlett, S. E. 12356 Rust, S. 12685 Ryan, C. A. 12947

S Saccomanno, L. 12605 Sage, J. R. 12905 Sakanaka, C. 12548 Sakellaris, H. 12828 Salovaara, R. 12661 Sanborn, J. R. 12275 Santamarina-Fojo, S.

12685 Santulli, R. J. 12257 Sauge-Merle, S. 12389 Saviola, B. J. 12844 Scarborough, R. M.

12257 Schade, M. 12465 Schaefer, B. C. 12691 Scheidig, C. 12743 Scheller, R. H. 12227 Schepp, W. 12778 Scherf, A. 12743 Schimmel, P. 12316 Schmieder, P. 12465 Schmitt, M. J. 12667 Schmutz, M. 12293 Schneewind, 0. 12424,

12839 Schoolnik, G. K. 12833 Schwartz, T. W. 12322 Schweiger, B. J. 12935 Schweizer, P. 12661 Scott, J. R. 12828 Sen, S. E. 12655 Shan, S.-o. 12299 Shea, J.-E. 12512 Shortman, K. 12697 Sieghart, W. 12905 Silver, P. A. 12542 Skaletskaya, A. 12536 Skibola, C. F. 12810 Smith, C. A. 12379 Smith, C. E. 12257 Smith, F. H. 12281 Smith, J. D. 12743 Smith, M. T. 12810 Smolak, P. J. 12379 Sollner, T. H. 12565,

12571 Somia, N. V. 12667 Souroujon, M. C. 12798 Spigelman, I. 12905 Spiller, B. 12305 Spirin, A. S. 12345 Stamler, J. S. 12760 Stein, R. C. 12589 Stevens, R. C. 12305 Stewart, C. L. 12595 Stribley, J. M. 12601

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Stubbe, J. A. 12339 Sugano, S. 12362 Suka, Y. 12356 Sun, L. 12844 Sun, S. 12299 Sun, Y. 12442 Suppes, P. 12953 Suter, M. 12697 Sutherland, R. M. 12703 Sutton, M. D. 12373 Sytwu, H.-K. 12970 Szabo, P. 12849

T Tang, Y. 12559 Taya, Y. 12384 Taylor, S. S. 12394 Tchernichovski, 0.

12901 Teague, T. K. 12691 Thatte, H. S. 12583 Thibodeaux, H. 12870 Thierry, A. R. 12293

Thirstrup, K. 12322 Thomas, C. 12855 Tian, N. 12911 Tiyanont, K. 12246 Tobin, E. M. 12362 Toma, J. 12970 Tomlinson, I. P. 12553 Ton-That, H. 12424 Townsend, R. R. 12589 Treiber, D. K. 12471 Tretter, V. 12905 Trinkaus, E. 12281 Tsien, R. W. 12893 Tsugeki, R. 12941 Tupler, R. 12650 Turner, C. J. 12465 Tyers, M. 12230

U Umeda, M. 12400

V Van Antwerp, D. 12667 van Bruggen, N. 12870

VanBuren, P. 12488 van Lookeren Campagne,

M. 12870 Vater, C. A. 12536 Velji, R. 12816 Venable, D. L. 12626 Verma, I. M. 12667 Vetter, D. E. 12667 Vogel, V. 12518 Volpin, H. 12275 von Hippel, P. H. 12448

w Wadsworth, S. 12816 Wahren, B. 12749 Walker, G. C. 12373 Wallen, K. 12965 Wang, H.-L. 12287 Wang, X. 12412 Warshaw, D. M. 12488 Wasan, H. 12553 Washington, M. T.

12224

Watanabe, S. 12536 Waterfield, M. D. 12589 Weber, T. 12565, 12571 Wei, C.-L. 12406 Weinberg, R. A. 12442 Weldon, P. J. 12246,

1,2251 Wermuth, N. 12273 Westermann, B. 12565 White, K. B. 12257 Whitten, D. G. 12287 Whyte, A. 12246, 12251 Wilcox, T. P. 12616 Wiley, D. C. 12379 Williams, L. T. 12548 Williams, S. P. 12870 Williamson, J. R. 12471 Wilson, L. 12459 Wilson, M. 12833 Wilson, R. C. 12790 Winkel-Shirley, B. 12929 Wong-Staal, F. 12749 Wright, N. A. 12553

Wu, G. 12798 Wudl, F. 12287

x Xu, L. 12548

y Yamanaka, K. 12436 Yang, G.-P. 12275 Yang, Z. 12251 Yang, Z.-C. 12246 Yi, X. 12412 Yokota, A. 12577 Yoshida, A. 12299

z Zhang, H.-C. 12257 Zhang, Q.-X. 12766 Zhou, H. 12816 Zhou, H. Z. 12798 Zhou, X. 12708 Zhu, Z.-Y. 12500 Zvelebil, M. J. 12589

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PNAS Information for Authors REVISED October 1999

PURPOSE AND SCOPE The Proceedings of the National Academy of Sciences USA (PNAS) publishes research reports, commentaries, perspectives, and colloquium papers. In accordance with the guiding princi- ples established by George Ellery Hale in 1914, PNAS publishes brief first announcements of Academy Members' and Foreign Associates' (hereafter referred to as Members) more important contributions to research and of work that appears to a Member to be of particular importance. PNAS is a general science journal with a broad scientific audience. All papers should be intelligible to this audience.

Research Reports describe the results of original research of exceptional importance.

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(x) Supplementary Material: Supplementary Material provides a way to enhance papers in PNAS by providing additional substantive data. Supplementary Material is reviewed along with the paper but instead of appearing in the printed version of the journal, it is distributed via the PNAS web site (www.pnas.org) at the time of publication. Supplementary Material is referred to at the appropriate point in the text and cannot be altered by authors after papers have been accepted.

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PROCEDURES FOR SUBMITTING MANUSCRIPTS Contact Information. Manuscripts should be sent to Proceedings of the National Academy of Sciences, 2101 Constitution Avenue, N.W., Washington, DC 20418 USA, or by courier or express mail to 1055 Thomas Jefferson Street, N.W., Suite 2013, Washington, DC 20007 USA. Phone 1-202-334-2672, fax 1-202-334-2739, e-mail [email protected].

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* The height in cm of each figure at desired printed size x 180 for a one-column figure or x 360 for a two-column figure, plus

* The height in number of lines of each table x 60 for a one-column table or x 120 for a two-column table, plus

* A 120-character allowance for the space above and below each single column of a figure, table, or equation, plus

* An additional 60 characters for each one-column line of equation.

* A table that has lines with more than 60 characters plus spaces or a figure that is wider than 8.7 cm takes up two columns in width.

If the word processing program character count excludes spaces, add the word count to the character count to obtain a character count that includes spaces.

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Classification: Select a major (Physical, Biological, or Social Sciences) and a minor category from the following. Dual clas- sifications are permitted between major categories and in excep-, tional cases, subject to Editorial Board approval, within a major category.

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Abstract. Provide an abstract of no more than 250 words on page 2 of the manuscript. Abstracts should explain to the general reader the major contributions of the article. References in the abstract must be cited in full.

I-, 2 0

PNAS I October 26, 1999 | vol. 96 | no. 22 | xv

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Page 7: Back Matter

Text. Describe procedures in sufficient detail so that the work can be repeated. Follow the spelling and usage given in Webster's Third New International Dictionary or the Random House Dic- tionary of the English Language. Avoid laboratory jargon. Correct chemical names should be given and strains of organisms should be specified. Trade names should be identified by an initial capital letter with the remainder of the name lowercase. Names and addresses of suppliers of uncommon reagents or instruments should be provided. Use Systeme International (SI) units and symbols whenever possible. When SI units are not used, the factor for conversion should be provided on first usage.

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References. References must be in PNAS style. Only published or in-press papers and books may be cited in the reference list. Abstracts of papers presented at meetings are not permitted. References should be cited in numerical order as they appear in text. Because tables and figures will be inserted in the text where first cited, references in these sections should be numbered accordingly. All authors (unless there are 10 or more) should be named in the citation. Databases are cited in the text or as footnotes.

The corresponding author must be prepared to provide a signed authorization for the citation of unpublished data and personal communications.

Journal articles are cited as follows:

10. Neuhaus, J.-M., Sitcher, L., Meins, F., Jr., & Boller, T. (1991) Proc. Natl. Acad. Sci. USA 88, 10362-10366.

For correct abbreviations of journal titles, refer to Chemical Abstracts Service Source Index (CASSI).

Articles or chapters in books are cited as follows:

14. Hill, A. V. S. (1991) in Molecular Evolution of the Major Histocom- patibility Complex, eds. Klein, J. & Klein, D. (Spiinger, Heidelberg), pp. 403-420.

Figure Legends. Provide these separately from the figures. Illustrations. Original drawings, high-quality photographs or

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xvi I www.pnas.org

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Page 8: Back Matter

PNAS Worksheet for Sizing Research Articles and Submission Checklist Please complete this form and submit it with your manuscript.

Author names:

Manuscript number (if known):

Research articles may be no morethan 47,000 characters, includingspaces, and thus may not exceed six printed pages. This count includes all text and the number of characters displaced by figures, tables, and equations. The total number of characters equals:

The number of characters including spaces in the text (include all parts except tables), plus

The height in cm of each figure at desired printed size* x 180 for a one-column figure or x 360 for a two-column figure, plus

The height in number of lines of each table including spaces x 60 for a one-column table or x 120 for a two-column table, plus

A 120-character allowance for space above and below each single column of a figure, table, or equation, plus

An additional 60 characters for each one-column line of equation.

A table that has lines with more than 60 characters plus spaces or a figure that is wider than 8.7 cm takes up two columns in width.

* If you are unable to submit figures at final size, please provide a photocopy of figures at final size and indicate desired reduction.

t Word processing programs differ in how they count characters: not all include spaces. Your character count must include spaces. If your character count excludes spaces, add the word count to the character count to obtain a character count that includes spaces. FOR MACs: For Word 5.1 and Freehand 6.0, the character count includes spaces. FOR PCs: For Word 97, select the character count that includes spaces. For Word versions 6 and 7 (for Windows 95) and WordPerfect 6, add the word count to the character count to obtain a character count that includes spaces. ForWordPerfect 5.2 and other programs (MAC or PC) that give only the word count, multiply the word count by 6.5 (the average number of characters per word including spaces) to obtain the total character count. If your program is not listed above, type a test phrase such as SUBMIT PAPER TO PNAS. If the character count is 21 (or 20), your program includes spaces and this is the number you should report; however, if you get 1 7 characters your program excludes spaces, and you must add the number of words to the number of characters.

t Authors may be responsible for additional charges incurred due to shortening papers in proof.

Character Count Form Please use the table below to calculate your character count and submit with your paper. Add extra figures and tables as needed. Does your word processing program count spaces?t [ Yes [ No (please add spaces)

Material Character Count All text characters (including title page, abstract, legends,

references) plus spaces ........................................................

Fig. 1 ( -column, cm high)g..............

Fig. 2 ( -column, cm high)g.............

Fig. 3 ( --column, - cm high)g.............

Fig. 4 ( -column, - cm high) .........................................

Fig. 5 ( -column, cm high)g.............

Table 1 ( -column, - lines high)g.............

Table 2 ( -column, - lines high)g.............

Table 3 ( -column, - lines high)g.............

Table 4 ( -column, - lines high)g.............

Equation(s) ..............................................................................

Space allowance

1 20 characters for each one-column figure, table, or equation

240 characters for each two-column figure, table, or equation

Total Characters in Paper (must not exceed 47,000)t.............

Sample Calculation Material Character Count All text characters (including title page, abstract, legends,

references) plus spaces ........................... ......... ... 25,660 Fig. 1 (1-column, 16 cm high = 180 x 16) 2,880 Fig. 2 (1 -column, 12 cm high = 180 x 12) 2,160 Fig. 3 (1 -column, 21 cm high = 180 x 21) .3,780 Fig. 4 (1-column, 11 cm high = 180 x 11) .1,980 Fig. 5 (2-column, 17 cm high = 360 x 17) .6,120 Table 1 (2-column, 23 lines high = 120 x 23) ......................... 2,760 Equation(s) [one 2-line and one 1 -line eq., 1 -col. (3 x 60)] .. 180 Space allowance

4 single-column figures (4 x 120) .. 480 1 double-column figure (1 x 240) ................................. 240 1 double-column table (1 x 240) ........................................... 240 2 single-column equations (2 x 120) ..................................... 240

Total Characters in Paper (must not exceed 47,000) ............... 46,720 I

Submission Checklist: O Five complete copies (six for Track 11 submissions) of the manuscript in final form, double-spaced, pages numbered. O One set of figures for the printer, four sets of high-quality figures, and one photocopied set of figures. O The final version of the text and any digital art and Supplementary Material forthe Web, each on separate computer disks. Identifythe platform, program, first author,

date, and file name on the disk label. O The completed Copyright Assignment/Documentation Report Form. O The character count breakdown of the final manuscript (see above). O The classification of the paper. O References according to PNAS style.

0

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Page 9: Back Matter

PNAS Copyright Assignment and Documentation Report Please complete this form and submit it with your manuscript.

Copyright Assignment In order that the Proceedings of the National Academy of Sciences USA (PNAS) may disseminate the WORK to the fullest extent, the author(s) hereby irrevo- cably grants, assigns, conveys, and transfers exclusively to the National Academy of Sciences (USA) the copyright in the WORK identified herein (including abstracts or summaries submitted with the WORK), under all laws, treaties, and conventions throughout the world in all forms, languages, and media now or hereafter known or developed without limitation in consideration of the pub- lication of the WORK in the PNAS.

The author(s) warrants that the WORK is original, that it has not been published, that the copyright interest has not been assigned, licensed, or otherwise transferred to another party, and that permissions have been ob- tained and are attached for any portions of the WORK subject to another copyright. Each author identified on the manuscript must sign this form. If any author's signature does not appear below, the signing author(s) represents and warrants that he or she signs this assignment as authorized agent(s) for and on behalf of all the authors and that this assignment is made on behalf of all the authors. The authors shall indemnify the Academy and/or its successors and assigns for any and all claims, costs and expenses, including attorney's fees, arising out of any breach of this warranty or other representations contained herein. This assignment is subject to the following conditions:

The author(s) reserves all proprietary rights, other than copyright, such as patent rights.

The author(s) reserves the right, after publication of the work in PNAS, to use all or part of the WORK in compilations or other publications of the author's own works, and to make copies of all or a part of the WORK for the author's use for lectures, classroom instruction, or similar uses.

If the WORK has been prepared by an employee within the scope of his or her employment, the employer reserves the right to make copies of the WORK for its own internal use.

Documentation Report If any of the following items are pertinent to your paper, we must receive the appropriate documentation or statements before we can publish your paper. Please check the appropriate boxes and sign below:

[J Structural Coordinate Deposition and Release. Authors of papers reporting new or revised structures must deposit their coordinates in the Protein Data Bank or an equivalent public archive, and the accession numbers must be supplied for publication. You agree, by signing below, that the coordinates will be released when the article is published. A footnote reporting the accession numbers will be added to your paper. You must provide the accession numbers on the page proof.

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[J Permission to Print Previously Published Material. If your paper includes material such as figures or tables that have been published previ- ously, whether or not you are an author of the earlier publication, you must provide us with the previous publisher's permission to republish this material in printand online. We acknowledge that copyright is held by the original publisher. Please let us know which items were published previously and where they appeared:

[J None of the 3 items above applies to this paper.

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Faculty Position Yale University

Department of Molecular Biophysics and Biochemistry

The Department of Molecular Biophysics and Bio- chemistry seeks applicants for a position at the assistant professor level in the area of molecular biophysics. Our department, which is located in both the Faculty of Arts & Sciences and the School of Medicine of the University, spans a broad range of areas including biochemistry, biophysical chem- istry, structural biology, molecular biology and molecular genetics. Applications should include a curriculum vita, a statement of research interests, three letters of reference, and reprints or preprints. Completed applications should be sent to:

Faculty Search Committee Department of Molecular Biophysics and

Biochemistry Yale University

260 Whitney Avenue, P.O. Box 208114 New Haven, CT 06520-8114 Telephone: (203) 432-5593

Application Deadline: December 1, 1999 Yale University is an Affirmative Action/Equal

Opportunity Employer.

POSTDOCTORAL RESEARCH FELLOWS in

VASCULAR BIOLOGY

Several positions are open for MD-PhD's in research related to nitric oxide action in smooth muscle cells, platelets, and atherosclerosis. Projects on calcium regulation, ion transporters/channels, oxidative stress, oxygen-derived free radicals and their roles in vascular diseases caused by hypercholesterolemia, diabetes, and hypertension.

C.V. and 3 letters of reference to: Dr. Richard A. Cohen Vascular Biology R408 Boston University School of Medicine 80 B. Concord St. Boston, MA 02 11 8

Editor-in-Chief The American Journal of Pathology

Term: July 1, 2000 to June 30, 2005

For five years, The American Journal of Pathology, a leading multidisciplinary journal with the latest research in the basic mechanisms of disease, has achieved the highest citation ranking of any general pathology journal (from ISI). The Editor-in-Chief will inherit the support of an experienced, centralized editorial office that facilitates the rapid review and efficient handling of more than 1,300 original manuscripts per year among geographically divergent editors.

Submit CV and Objectives To: Dorothy Bainton, M.D., Search Committee Chair c/o American Society for Investigative Pathology

9650 Rockville Pike Bethesda, Maryland 20814-3993

For more information go to http. //asip. uthscsa. edu/eicad. html

Application Deadline: November 15, 1999

Classified Ads Advertise positions, meetings, and fellow- ships through the PNAS Classified Ads.

Classified Rates Full Page (7" x 10") $990 Half Page (Vertical 3 3/8 X 10XI;

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National Academy of Sciences Members should contact Joanne D'Amico at PNAS for special discounts (Phone: 1 -202-334-2672; Fax: 1 -202-334-2739; E-mail: [email protected]).

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Page 11: Back Matter

NATIONAL ACADEMY OF SCIENCES COLLOQUIUM 5 VIRULENCE AND DEFENSE IN HOST-PATHOGEN INTERACTIONS

COMMON FEATURES BETWEEN PLANTS AND ANIMALS

DECEMBER 9-11, 1999 The Arnold and Mabel Beckman Center, Irvine, California

Organized by Noel T. Keen, R. James Cook, Brian J. Staskawicz, John J. Mekalanos and Fredrick M. Ausubel

Virulence Mechanisms in Pathogens Jorge Galan, Yale Univ. School of Medicine, Modulation of the host- cell actin cytoskeleton by the Salmonella type Ill secretion system

Frances Jurnak, UC Irvine, Structure and function of pectic enzymes-- -virulence factors of plant pathogens

Dan Portnoy, UC Berkeley, Pathogenicity and immunogenicity of Listeria monocytogenes

Alan Collmer, Cornell University, Type 1ll mediated translocation of plant effectors by Pseudomonas syringae

Guy Cornelis, Catholic University, Brussels, Belgium. Type 1ll secretion and translocation of Yersinia Yops

Ulla Bonas, Univ. of Halle, Germany, Type 1ll secretion and targeting of bacterial proteins from plant and animal pathogens by Xanthomonas campestris pv. Vesicatoria

Jeff Miller, UCLA, Signal transduction during the Bordetella infectious cyc/e

Lory Rahme, Harvard University, Multihost pathogenesis systems- Pseudomonas aeruginosa-Coenorhabditis elegans interactive genetics

Peter Greenberg, Univ. of Iowa, Communication systems and group behavior in Pseudomonas aeruginosa

William Goldman, Washington Univ., St. Louis, Fungal-host interactions as exemplified by Histoplasma capsulatum

Brett Finlay, Univ. of British Columbia, Enteropathogenic E. coli

David Relman, Stanford Univ., Global host gene expression responses during infection

Active Defense Mechanisms in Hosts Kathryn Anderson, Sloan Kettering Inst., Drosophila Toll receptor pathwaj

Jonathan Jones, John Innes Inst., England, Role of toll-like proteins in disease resistance of plants

Charles Janeway, Howard Hughes Medical Inst., Yale Univ., Mammalian Toll-like receptor pathways

Gourisankar Ghosh, UC San Diego, The NF-kB pathway in Vertebrates

Jeff Dangl, Univ. North Carolina, Perception of pathogen signals by plants

Gerry Pier, Harvard University, Innate defense mechanisms on mucosal surfaces

Matthew Mulvey, Washington Univ. School of Medicine, St. Louis, Innate Host defenses against uropathogenic E. coli

Greg Martin, Boyce Thompson Inst., Cornell Univ., Pathogen recognition and signal transduction mediated by the product of the Pto disease resistance gene

Carl Nathan, Weill Medical College, Cornell Univ., New York City, Reactive oxygen and nitrogen species in animal defense: mechanisms of microbial resistance

Dan Klessig, Rutgers University, NO and salicylic acid signaling in plant defense

Robert Hancock, University of British Columbia, Antimicrobial peptides in animal defense

Bud Ryan, Washington State Univ., Defense signaling and response pathways in plants against pests

Keynote address, David Baltimore, president, California Institute of Technology, Isn't Microbiology out-dated?

Name Affiliation ___________________Position _____________________

A ddress __ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ city __ _ _ _ _ _ _ _ _ State _ __ Zip _ _ _ _ _

Phone __ _ _ _ _ _ _ _ Fax __ _ _ _ _ _ _ _ E-m ail Address _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _

MAIL THIS FORM WITH PAYMENT TO: A

Nationwald Acadtemy ofAScience REGISTRATION FEE (non-refundable/can be transferred), National Academy of Sciences ~~~~including meals: 2 101 Constitution Ave, NW $150 General Participant $50 Graduate Student Washington, DC 20418 Fax (credit card only): 202-334-2153 PAYMENT: Check or Credit Card

Circle One: VISA Amer. Express MasterCard For additional information, Card #:________________Expires:___

E-mail: [email protected] Sintr:Date:_____ Web: www.nas.edu/nas/co11oquiaSintr:_ __

Space for th'is meeti'ng i's l'imi'ted, so please regi'ster early

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Page 12: Back Matter

National Academy of Sciences Colloquium Variation and Evolution in Plants and Microorganisms

Toward a New Synthesis 50 Years after Stebbins

X' " 1? Z JANUARY 27-29, 2000

4,+ '1 ~ ~The Arnold and Mabel Beckman Center, Irvine, California )UNDED 3 Organized by Francisco J. Ayala, Walter M Fitch, and Michael T. Clegg

Session 1. Early Prokaryote Evolution Walter M. Fitch, University of Califomia, Irvine Predicting the Course of Evolution: Viral Models

Bruce Levin, Emory, Atlanta Genetic Variation and the Response of Bacteria to Natural and Not-So-Natural Selection

Andres Moya, University of Valencia, Spain The Evolution of RNA Viruses: A Population Genetics View

Lynn Margulis, University of Massachusetts, Amherst Endosymbiosis in Eukaryotic Evolution

Session 11. Origins and Evolution in Eukaryote Cells Jeffrey Palmer, Indiana University, Bloomington Evolutionary Mobility of Organelle Genes-Migration to the Nucleus and Lateral Transfer between Organisms

Nina Fedoroff, Penn State University Transposable Elements in Plants

Larry Simpson, University of California, Los Angeles Evolution of RNA Editing in Kinetoplastid Protozoa.

Francisco J. Ayala, University of Califomia, Irvine Evolution and Population Structure of Plasmodium

Session 111. Patterns of Plant Evolution

David L. Dilcher, University of Florida, Gainesville Major Evolutionary Trends in Plants: The Fossil Record

Pamela S. Soltis, Washington State University, Pullman Polyploid Evolution: Genetic and Genomic Consequences

Brandon S. Gaut, University of California, Irvine Rates of Genome Evolution in Plants

Michael T. Clegg, University of California, Riverside Gene Evolution in Plants

Session IV. Population Variation and Adaptation Barbara A. Schaal, Washington University, St. Louis Variation in Plant Populations

Kent E. Holsinger, University of Connecticut, Storrs Mating and Breeding Systems in Plant Evolution

Norman C. Elistrand, University of California, Riverside Hybridization as Stimulus for the Evolution of Invasive Success in Exotic Plants

Jared M. Diamond, University of Califomia, Los Angeles Origins of Domesticated Plants

Banquet Lecture J. William Schopf, University of California, Los Angeles Early Life

Name Affiliation Position

Address City State Zip

Phone Fax E-Mail Address

MAIL THIS FORM WITH PAYMENT TO: A

Edward Patte | REGISTRATION FEE (non-refundable/can be transferred), National Academy of Sciences, NAS-146 including meals: 2101 Constitution Ave, NW $75 General Participant (before 12/1 99) Washington, DC 20418 $185 General Participant (after 12/1/99) Fax (credit card only): 202-334-2153

PAYMENT: Check or Credit Card

For additional information, Circle One: VISA Amer. Express MasterCard

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Signature: Date:

NAS will supplement expenses of registered graduate students and postdocs Up to $100 for hotel costs and $150 for air travel!

Space for this meeting is limited, so please register early. Reduced fee before December 1.

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Page 13: Back Matter

NATIONAL ACADEMY OF SCIENCES COLLOQUIUM

AUDITORY NEUROSCIENCE: f 9iX3, DEVELOPMENT, TRANSDUCTION, AND INTEGRATION

19-21 MAY2000

The Arnold and Mabel Beckman Center, Irvine, California

Organized by A. J. Hudspeth (Howard Hughes Medical Institute and The Rockefeller University) and Masakazu Konishi (California Institute of Technology)

Development and Regeneration of the Inner Ear

Doris K. Wu, National Institutes of Health - Patterning of the inner ear

Julian Lewis, University College London, England - The development of sensory patches: hearing lessons from the fly

Donna M. Fekete, Purdue University - Molecular genetics of pattem formation in the developing inner ear

Richard A. Baird, Washington University School of Medicine - Hair-cell repair and regeneration in normal and mitotically-blocked saccular cultures

Jennifer S. Stone, University of Washington School of Medicine - Mechanisms of sensory cell production during regeneration in the mature chick inner ear

Jeffrey T. Corwin, University of Virginia School of Medicine - Arousing the progenitors of mammalian hair cells

Transduction, Adaptation, and Mechanical Amplification by Hair Cells

Geoffrey A. Manley, Technische Universitat MOnchen, Germany - Cochlear mechanisms from a phylogenetic viewpoint

Mario A. Ruggero, Northwestern University - Mechanics of the mammalian cochlea

Ian J. Russell, University of Sussex, England - Spatial and temporal representation of a tone on the guinea pig basilar membrane

Jonathan F. Ashmore, University College London, England - Molecular mechanisms in sound amplification in the mammalian cochlea

Graeme Yates, University of Western Australia, Australia - Linking mechanical sensory transduction to the cochlear motor

David P. Corey, Harvard Medical School - Sensory adaptation by hair cells

Coding in the Auditory Central Nervous System

Eric D. Young, Johns Hopkins University School of Medicine - What does a receptive field mean? Insights from the dorsal cochlear nucleus

Donata Oertel, University of Wisconsin - Madison - Detection of synchrony in the activity of auditory nerve fibers by octopus cells of the mammalian cochlear nucleus

Masakazu Konishi, California Institute of Technology - Cellular mechanisms for resolving phase ambiguity in the owl's inferior coiculus

Jon H. Kaas, Vanderbilt University - Subdivisions of auditory cortex and processing streams in primates

Josef P. Rauschecker, Georgetown University Medical Center - Parallel processing in the auditory cortex of human and nonhuman primates

Nobuo Suga, Washington University - The corticofugal system for hearing

Coding and Plasticity in the Auditory Central Nervous System

Eric 1. Knudsen, Stanford University School of Medicine - Mechanisms of adaptive plasticity in the owl's auditory localization pathway

Gregg H. Recanzone, University of California, Davis - Cortical processing of sound location and temporal order

Andrew J. King, Oxford University, England - Plasticity in the neural coding of auditory space in the mammalian brain

Allison J. Doupe, University of California, San Francisco - Neural learning of birdsong

Xiaoqin Wang, Johns Hopkins University School of Medicine - Cortical mechanisms underlying vocal communication in primates

Patricia Kuhl, University of Washington - Early experience and language development. reinterpreting the critical period

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